Research Assistant within T cell phenotypes in MS development

Do you want to contribute to top quality medical research?

In our lab we combine human immunology and rodent systems to dissect the effect of genetics, metabolism and environmental factors on immune cell modulation in the context of autoimmunity. We offer a vibrant research environment, diverse expertise and a highly collaborative structure.

Your mission

As research assistant, your mission will be to develop CRISPR-mediated approaches to modulate T cell function in the MS animal model EAE. Daily chores will include plasmid cloning in bacteria, plasmid purification, retrovirus generation and concentration, mouse immunizations, infection of mouse T cells in vitro, adoptive transfer of cells into target animals and daily EAE scoring.

Your profile

You should be an independent and driven individual with a strong background in cellular and molecular biology and immunology with experience in handling mice and rats. Flow cytometry is a requisite. Experience in CNS tissue dissection and processing for downstream applications is an advantage. Good proficiency of the English language and team-working capacity are a must.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

Read more about the Department of Clinical Neuroscience
Read more about the research group you will be part of

Application

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Want to make a difference? Join us and contribute to better health for all!

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