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Located in the Campus Lengg of the University of Zurich, and soon in the newly built research tower of the Kinderspital, we apply and develop state-of-the-art technologies including single cell analytics, CRISPR-based genome editing, machine learning algorithms, high content data analysis and ex-vivo / in vivo PDX models. We are embedded in a strong precision oncology network at UZH with strong ties with the ETH Zurich and are centrally involved in international clinical trials for childhood leukemia providing a relevant context to our research program.The employment is limited to 2 years with the option of extension.

Your responsibilities

  • You explore the cell biology of various cell death pathways (apoptosis, pyroptosis, necroptosis, ferroptosis) and their potential to eradicate resistant disease in the context of acute leukemia of childhood.
  • You dissect the relationship between intrinsic and extrinsic signaling programs using a representative xenograft bank of primary leukemia.
  • You Investigate the immunogenic aspect of programmed cell death instances.
  • You work in an agile and collaborative lab environment and contribute to scientific discovery.
  • You will apply state-of-the-art laboratory methodologies.
  • You are receptive for encouragement and support for innovative and actionable ideas.
  • You have the opportunity to work in a multidisciplinary environment with molecular and cellular biologists, clinicians, computer scientists, and international collaborators.

Your profile

  • You have a strong appetite for scientific discovery and a strong interest in disease modeling, cell death research, and biomedical computing.
  • You have a strong experimental track record.
  • You are motivated to work together with a focused task force and to guide master and PhD students.
  • You hold an MD-PhD or PhD in biological or biomedical sciences or equivalent.
  • You have strong analytical and problem-solving skills and are comfortable with planning, prioritizing, conducting, analyzing and communicating research in a variety of contexts.
  • You communicate actively with collaborators, colleagues and team members with proficiency in English.

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